Research Blog

Cardarine GW-501516 Endurance

Cardarine (GW-501516): PPARδ Agonist Research Profile

Cardarine (GW-501516) is a PPARδ agonist — not technically a SARM — studied for its effects on fatty acid oxidation, mitochondrial biogenesis, and endurance. This profile covers the research, including GSK's discontinuation decision.

20 Feb 2026 · 5 min read

Peptides Melanocortin MC1R

Melanotan I (Afamelanotide): MC1R-Selective Pigmentation Research

Melanotan I (afamelanotide) is a selective MC1R agonist that has advanced furthest through clinical development of all melanocortin analogues, achieving regulatory approval in Europe for erythropoietic protoporphyria.

17 Feb 2026 · 6 min read

SARMs Ostarine MK-2866

Ostarine (MK-2866): The Most-Studied SARM in Research

Ostarine (MK-2866 / Enobosarm) has more published human trial data than any other SARM, having progressed through Phase II and Phase III cancer cachexia trials. This guide covers the research evidence.

16 Feb 2026 · 5 min read

Peptides Melanocortin Research

Melanotan II (MT-2): Melanocortin System Research

Melanotan II is a synthetic cyclic heptapeptide analogue of alpha-MSH acting at melanocortin receptors. Research has examined its roles in pigmentation, sexual function, and appetite regulation across multiple preclinical and clinical studies.

14 Feb 2026 · 7 min read

Growth Hormone MK-677 Research Guide

MK-677 (Ibutamoren): Growth Hormone Secretagogue Research Profile

MK-677 is a non-peptide ghrelin mimetic that stimulates GH and IGF-1 secretion without suppressing testosterone. This profile covers the mechanism, Murphy 1998 trial data, and compound details.

12 Feb 2026 · 5 min read

Peptides Growth Hormone GHRP

GHRP-6: Growth Hormone Releasing Peptide Research Overview

GHRP-6 was among the first synthetic growth hormone secretagogues to be characterised. This article covers its pharmacology, comparison to newer GHRPs, and its role in GH axis and appetite research.

11 Feb 2026 · 6 min read

Peptides Growth Hormone GHRH

CJC-1295 with DAC: Long-Acting GHRH Analogue Research

CJC-1295 with DAC extends the half-life of Modified GRF 1-29 to approximately 6–8 days via covalent albumin binding. This article reviews the pharmacokinetics, published human data, and research applications of this long-acting GHRH analogue.

08 Feb 2026 · 6 min read

SARMs LGD-4033 Research Guide

LGD-4033 (Ligandrol): Research Compound Profile

LGD-4033 has the most robust human pharmacokinetic data of any SARM following the landmark 2013 Basaria et al. Phase I trial. This profile covers mechanism, trial findings, and research details.

08 Feb 2026 · 5 min read

Peptides Growth Hormone GHRP

Ipamorelin and CJC-1295 (No DAC): Growth Hormone Research

Ipamorelin is a selective growth hormone secretagogue; CJC-1295 without DAC (Mod GRF 1-29) is a GHRH analogue. Together they are among the most widely studied peptide combinations in GH axis research.

05 Feb 2026 · 7 min read

SARMs RAD-140 Research Guide

RAD-140 (Testolone): Research Compound Profile

RAD-140 is one of the most potent SARMs in research, demonstrating high anabolic selectivity with very low androgenic activity in preclinical models. This profile covers mechanism, trial data, and compound details.

04 Feb 2026 · 5 min read

Peptides NAD+ Longevity

NAD+: Nicotinamide Adenine Dinucleotide — Research Overview

NAD+ is a coenzyme central to cellular energy metabolism and DNA repair. Research into its precursors and direct supplementation has expanded rapidly, with studies examining roles in ageing, mitochondrial function, and neuroprotection.

02 Feb 2026 · 7 min read

SARMs Education Research Guide

What Are SARMs? A Complete Research Guide

SARMs — Selective Androgen Receptor Modulators — are a class of compounds researched for their tissue-selective activity at the androgen receptor. This guide explains how they work, what the research shows, and their legal status in the UK.

31 Jan 2026 · 6 min read